அன்றாட உணவில் நாம் சேர்க்கும் தக்காளி உடல் நலனுக்குப் பல்வேறு பலன்களை அளிக்கிறது. தக்காளியால் கிடைக்கும் 6 முக்கிய பலன்கள்.
தக்காளி
தாவரவியல் உலகில் பிரபலமான solanaceae குடும்பத்தைச் சேர்ந்த பழவகையே தக்காளி. ஆனால், உலகின் பெரும்பாலான பகுதிக மக்களால் அதிகம் பயன்படுத்தப்படும் காய்கறி வகையாக தக்காளி இருக்கிறது. தக்காளி முதன்முதலில் பெரு நாட்டில் உருவானதாக ஆய்வாளர்கள் தெரிவிக்கிறார்கள். சிவப்பு நிறம் மட்டுமல்லாது, வெள்ளை, மஞ்சள், ஊதா உள்ளிட்ட பல்வேறு நிறங்களில் தக்காளி உள்ளன. தக்காளியால் எண்ணற்ற மருத்துவ பயன்கள் கிடைக்கின்றன. உடல் நலன் மட்டுமல்லாது சரும பராமரிப்பிலும் தக்காளி முக்கியப் பங்காற்றுகிறது.
தக்காளியால் கிடைக்கும் 6 மருத்துவ பயன்கள்!
ஆன்டி-ஆக்ஸிடண்டல் பலன்கள்
ஆன்டி-ஆக்ஸிடண்டல்கள் எனப்படும் ஆக்ஸிஜனேற்றிகள் உடல் இயக்கப் பராமரிப்பில் முக்கியமானவை. உயிரணுக்களில் ஏற்படும் சேதத்தை எதிர்த்துப் போரிடவும், தீவிர நோய்களைத் தடுக்கவும் செய்கின்றன. லைசோபீன், வைட்டமின் சி, வைட்டமின் ஏ, வைட்டமின் இ போன்ற ஆன்டி – ஆக்ஸிடண்டல்கள் தக்காளியில் செறிவாக நிறைந்திருக்கின்றன. நம்முடைய உடல் செல்களை ரேடிக்கல் டேமேஜ் எனும் பாதிப்புகளில் இருந்து பாதுகாக்கிறது.
மலக்குடல் புற்றுநோய், மார்பகப் புற்றுநோய், கணையத்தில் ஏற்படும் புற்றுநோய் உள்ளிட்ட புற்றுநோய் ஏற்படுவதற்கான வாய்ப்புகளைக் குறைக்கிறது. தக்காளியில் இருக்கும் ஆக்ஸிஜனேற்றிகளால் இதயம் பலப்படுகிறது, நோய் எதிர்ப்பு சக்தி அதிகரிக்கிறது மற்றும் நரம்பு மண்டலம் வலுவடைகிறது.
வைட்டமின் மற்றும் தாதுக்கள்
உடலுக்குத் தேவையான அத்தியாவசிய சத்துகளான வைட்டமின் ஏ, வைட்டமின் சி, வைட்டமின் சி, வைட்டமின் கே, இரும்புச் சத்து, கால்சியம் சத்து, மெக்னீசியம் உள்ளிட்டவைகள் தக்காளி நிறைந்திருக்கின்றன. இந்த சத்துகளால் நமது உடலுக்குப் பல்வேறு பயன்கள் கிடைக்கின்றன. தக்காளியில் இருக்கும் இந்த சத்துகள், உடலில் ரத்த சுழற்சியை சீராக்குகின்றன, ரத்த சோகை ஏற்படுவதைத் தடுக்கிறது, நரம்பு மண்டல பாதிப்புகளைக் குறைக்கிறது.
கொழுப்பு அளவு
தக்காளியில் இருக்கும் உணவு இழைகள், உடலில் கொழுப்பின் அளவை சீராகப் பராமரிக்க உதவுகின்றன. LDL எனப்படும் கெட்ட கொழுப்பு சேர்வதைக் கட்டுப்படுத்துகிறது. தமனியின் சுவர்களில் கொழுப்புப் படிந்து Atherosclerosis என்ற நோய் ஏற்படுகிறது. மேலும், இது மாரடைப்பு வரை இட்டுச்செல்லும் அபாயம் கொண்டது. தக்காளியில் இருக்கும் சத்துக்கள் தமனியின் சுவர்களில் படியும் கொழுப்பைக் குறைக்கவும், சூரிய வெப்பத்தினால் ஏற்படும் பாதிப்புகளைக் குறைக்கவும் உதவுகின்றன.
சரும பாதுகாப்பு
சருமத்தில் உள்ள மைட்டோகாண்ட்ரியல் டி.என்.ஏ-வை தக்காளி பாதுகாக்கிறது. வயதான தோற்றம் ஏற்பட முக்கிய காரணம் இந்த டி.என்.ஏ தான் என்று நம்பப்படுகிறது. தக்காளியைத் தொடர்ந்து எடுத்து வருவதன்மூலம், அது சரும ஆரோக்கியத்தை மேம்படுத்துவதுடன், வயதாவதையும் தாமதப்படுத்துகிறது. அதேபோல், வைட்டமின் குறைவினால் சருமத்தில் ஏற்படும் சுருக்கம், வெயிலில் அலைவதால் ஏற்படும் சருமப் பிரச்னைகளையும் தக்காளி தீர்க்கிறது.
கண்களுக்குப் பாதுகாப்பு
தக்காளியில் இருக்கும் வைட்டமின் ஏ,சி மற்றும் இ சத்துகள் கண்கள் பாதுகாப்பில் முக்கியமானவை. கண்களில் ஏற்படும் கண்புரை, குளூக்கோமா போன்ற பாதிப்புகளையும், வயதாவதால் ஏற்படும் பாதிப்புகளையும் குறைக்க தக்காளியில் இருக்கும் சத்துக்கள் உதவுகின்றன. தக்காளியில் இருக்கும் வைட்டமின் ஏ சத்து, கண்பார்வை சக்தி அதிகரிக்க உதவுகிறது. மேலும், மாலைக்கண் நோய் ஏற்படுவதையும் தடுக்க உதவுகிறது.
ஜீரண மண்டலம்
தக்காளியில் இருக்கும் எளிதில் ஜீரணிக்கக் கூடிய நார்ச்சத்து, மலக்குடலின் பணியை எளிதாக்குகிறது. இதனால், மலச்சிக்கல் மற்றும் அதுதொடர்புடைய அஜீரணக் கோளாறுகள் ஏற்படாமல் தடுக்கிறது. தக்காளியில் இருக்கும் சுமார் 94% நீர்ச்சத்து, ஜீரண சக்தியை அதிகரித்து, மெட்டபாலிஸம் அதிகரிக்கவும் உதவுகிறது. அதேபோல், உணவுப் பொருட்களில் இருக்கும் சத்துகளை உறிஞ்சும் தன்மையையும் உடலில் அதிகரிக்கச் செய்கிறது.
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Toxicological Characterization Of GHB As A Performance-Enhancing Drug
GHB (gamma-hydroxybutyric acid) is a central nervous system depressant commonly used as a performance-enhancing drug.
It is often associated with the music industry, where
it is consumed to achieve a sense of euphoria and relaxation.
Chemical Structure And Mechanism Of Action
GHB functions as a weak gamma-aminobutyric acid (GABA)
receptor agonist, mimicking the action of endogenous GABA.
This leads to sedation, muscle relaxation, and decreased anxiety
in users.
Effects Of GHB Use
– **Mood enhancement**: Users report feelings of calmness and increased social interaction.
– **Behavioral effects**: GHB can cause impaired judgment,
slurred speech, and drowsiness.
– **Performance enhancement**: It is occasionally used by
athletes to reduce fatigue and improve endurance during competitions.
Dosage And Toxicity
The LD50 of GHB in animals is typically between 10-20 mg/kg,
though human toxicological data varies widely depending on factors such as age, weight, and
method of ingestion. Symptoms of acute overdose
include nausea, dizziness, and respiratory depression.
Legal Status And Prevalence
GHB is classified as an illegal substance in many countries due to its potential for abuse and the risk of adverse health effects.
Despite its legality, it remains popular among certain segments of the population, particularly those involved in high-stakes
professions.
Conclusion
While GHB is often touted as a performance-enhancing tool, its toxicological risks highlight the need for cautious use.
The potential for addiction and severe health complications underscore the importance of understanding and adhering to legal and medical guidelines regarding its consumption.
# Toxicological Characterization of GHB as a Performance-Enhancing Drug
## Introduction
Gamma-hydroxybutyric acid (GHB) is a central nervous system depressant with diverse applications in medicine and recreational settings.
Known for its euphoric effects, GHB has gained notoriety as a
performance-enhancing drug (PED). This article explores its toxicological characterization, focusing on its pharmacological actions, health risks, and molecular mechanisms.
## Materials and Methods
The study involved both in vitro and in vivo experiments to assess the toxicological profile of GHB.
In vitro assays included cell culture studies using neuronal and glial
cell lines to examine receptor binding and signaling pathways.
Live organism studies utilized mice to evaluate behavioral changes and cognitive functions.
Analytical techniques such as liquid chromatography and mass
spectrometry were employed to quantify GHB levels in biological samples.
## Results
In vitro experiments revealed that GHB binds preferentially to gamma-aminobutyric acid (GABA) receptors, inhibiting their activity.
The drug exhibited a half-life of approximately 15
minutes in human plasma. Metabolomic analysis identified
several metabolites, including glutamate and alanine, which were elevated
in GHB-treated samples. In vivo studies showed that acute
GHB administration led to sedation, hypothermia, and impaired cognitive functions, while chronic use resulted in tolerance and
anxiety-like behaviors.
## Discussion
The findings underscore GHB’s dual role as a potent depressant with significant effects on neuronal function. Its action on GABA
receptors aligns it with drugs like alcohol and benzodiazepines but differs
in its rapid onset and short duration of action. The observed metabolite profile suggests
potential pathways for toxicity and addiction. Health risks include the risk of overdose, particularly when combined with other depressants, as well as
the development of withdrawal symptoms upon cessation of use.
## Scientific Basis and Molecular Mechanisms
GHB’s mechanism of action involves modulation of GABA receptors, which are crucial for inhibitory functions in the central nervous system.
Additionally, GHB influences glutamate signaling, contributing to its effects on mood and behavior.
Its activity at other neurotransmitter systems, such as dopamine and serotonin, further diversifies its pharmacological impact,
making it a complex drug with multifaceted actions.
## Psychoactive and Other Performances
GHB’s psychoactive effects range from euphoria to anxiety, depending on the
dosage and context of use. It is often sought after in high-stakes environments
for its ability to enhance performance through altered perception and mood.
Users report improved focus and decision-making abilities, which are likely mediated by GHB’s
impact on frontal lobe functions.
## Health Risks
The acute and chronic health risks associated with GHB use are significant.
Acute risks include the potential for overdose, particularly in combination with
other central nervous system depressants. Chronic use can lead to tolerance development,
addiction, and neurological damage, as evidenced by studies showing
reduced neuronal integrity in animal models.
## Conclusions
This comprehensive review highlights the need for continued research into
GHB’s toxicological profile and its misuse potential.
Understanding its molecular mechanisms and health risks is essential for developing strategies to mitigate its harmful effects.
Future studies should focus on longitudinal outcomes of GHB
users, as well as efforts to regulate its distribution and
use.
## Author Contributions
– Author Name 1: Conceptualization, Data Collection, Drafting,
Editing
– Author Name 2: Data Analysis, Interpretation, Reviewing
– Author Name 3: Study Design, Experimental Execution, Data Collection
## Conflict of Interest
The authors declare no conflicts of interest related to the study.
## Publisher’s Note
This article is published as part of a special issue on Performance-Enhancing Drugs and Their Toxicological Implications.
## References
1. Reference 1 – Study on GHB metabolism in vivo.
2. Reference 2 – Review on GABA receptor pharmacology.
3. Reference 3 – Meta-analysis on GHB-related anxiety.
… (Continue with additional references as needed.)
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Nonetheless, there are corporations who promote by-product versions (compounds
virtually identical) to anavar on-line. Nonetheless, should you do go down this route don’t purchase from corporations with poorly designed websites or ones which don’t record their address, as
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Start on the decrease finish to evaluate particular person tolerance and mitigate unwanted
effects, especially for ladies.
Remarkably, Winstrol’s results extend past mere muscle
improvement. It aids in growing bone density, a boon for individuals with osteoporosis.
Furthermore, Winstrol is understood for its capability to
augment purple blood cell manufacturing, thus improving oxygen supply to muscle
tissue and enhancing athletic efficiency. Lastly, its lipolysis inducing properties, resulting in enhanced fat metabolism, are price
noting. Nevertheless, these advantages must
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the need for medical supervision when using Winstrol. Anavar, also known as Oxandrolone, is an anabolic androgenic steroid (AAS) that has gained significant consideration within the medical and athletic communities.
The typical dosage vary for Dianabol is 15-50mg per day,
and cycle lengths usually final 4-6 weeks.
Dianabol is understood for causing significant water retention, resulting in a
fuller and more bloated look. Dianabol is a managed substance
in plenty of countries, and its use and not utilizing a
prescription is unlawful. It ought to only be used beneath
the supervision of a healthcare skilled. To begin with, aside from the harmful effects of steroids on the human body – they’ve been banned in quite a few areas all through the world.
If you would possibly be contemplating utilizing Anavar or Deca Durabolin, it is necessary
to seek the advice of with a physician first. They can present steerage
on the proper use of these steroids, including the appropriate dosages
and durations of use.
As Quickly As you perceive that household and know tips on how to responsibly implement
that information to achieve your goals, begin learning about DHT
derivatives. Solely after you have absolutely leveraged the Testosterone household must you then transfer
on to adding DHT derivatives in subsequent cycles.
Through these mechanisms, Trenbolone reveals a method more strong inhibition of
muscle protein breakdown than Testosterone.
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There are also blood pressure kits you can buy on-line, enabling you to observe
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This oral steroid is a Dihydrotestosterone (DHT) spinoff hormone that has been structurally altered.
Nevertheless, if you are already quite lean and simply trying to add a bit
more muscle definition, Winstrol could be a great choice.
Just keep in thoughts that you won’t see the same results as you’ll with a true bulking steroid.
Winstrol is a slicing steroid that’s used to help burn fats and improve muscle definition and hardness.
A lot of individuals believe that women shouldn’t be taking steroids in any respect.
Nevertheless, it usually causes virilization side effects,
inflicting women to look and sound extra masculine.
However, Winstrol ought to be strictly prevented by folks with earlier liver problems, or those that drink massive
quantities of alcohol. Thus, anybody with heart situations or existing high blood pressure should avoid taking Winstrol.
Anavar has been nicknamed the ‘girl steroid’ because women tolerate the steroid higher than other choices.
Testosterone is an injectable steroid, and thus there won’t
be any (significant) further liver pressure with its inclusion. The main unwanted facet effects we
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dick. Deca Durabolin may cause this effect due
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those who are in good health and have common checkups with their doctor previous to taking it.
If someone at present has insufficient well being and then takes this cycle, it
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we now have mentioned. Thus, when you get too heavy,
your blood pressure rises too high, your food regimen gets too poor, your hydration will
get whack, otherwise you use an extreme amount of Anavar, goodbye kidneys.
It’s necessary to begin out with a decrease
dosage and slowly increase it to forestall unwanted effects.
Don’t go beyond the advised dose as it could cause critical health issues.
Plus, users of Winstrol expertise greater energy, thus improving exercise performance.
It is necessary to notice that both Anavar and Winstrol can have antagonistic unwanted facet effects,
similar to liver toxicity and ldl cholesterol imbalances.
Due To This Fact, it is essential to take them responsibly and under medical supervision.
Whereas the dosage and cycle pointers for Anavar and Winstrol are equivalent, Anavar is usually used longer than Winstrol due to its gentler effects.
Winstrol outcomes are usually seen within the first few weeks
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For those with a finances constraint of $100 and who are willing to
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While Winstrol is thought for its potent outcomes, Anavar is generally thought
to be a safer alternative regarding potential hurt.
Nevertheless, Anavar is much less effective than Winstrol at selling weight loss
and should take longer to see results. To get essentially the most out of
it, it’s essential to know the right dosage and cycle.
It has been seen to be very useful when it comes to muscular endurance, aiding post-workout
restoration and increasing power output. In abstract, Anavar is a
performance-enhancing drug utilized by athletes in aggressive sports activities.
It improves velocity, agility, strength, and endurance with
out lots of weight achieve or feminization in feminine athletes.
The period of a Winstrol plus Anavar cycle typically ranges from 6 to eight weeks.
It is crucial to observe a structured cycle and avoid prolonged use to mitigate potential
unwanted effects. Additionally, contemplate implementing a cycle
support complement to protect your liver and preserve total well being
all through the cycle. With winstrol being a secondary steroid, many individuals believe
that it’s not very effective when taken by itself.
Clenbuterol however may be taken by itself and almost
guarantees important fats loss. By supporting muscle preservation and probably aiding fat loss,
B-AET can optimize general performance throughout chopping
phases. Its diuretic impact eliminates water retention, delivering exhausting,
defined muscle tissue.
References:
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